kyle Gillet

The Women's Hormone Masterclass with Dr. Kyle Gillett: A Deep Dive Into Testosterone, Dutasteride, SHBG, & Menopause Weight Gain

Dr. Kyle Gillett enjoys providing holistic individualized care to his patients. His practice includes preventative medicine, aesthetics, sports medicine, hormone optimization, obstetrics and infertility, integrative medicine, and precision medicine including genomics. He believes that each human is a unique creation that requires attention to their body, mind, and soul. He uses shared decision-making and an evidence-based approach. He firmly believes "food is medicine" and "exercise is medicine". Dr. Gillett describes the "7 pillars of health": exercise, diet, sleep, stress, social, sunlight, and spirit. These are more powerful than any medication or supplement. He enjoys spending time outdoors on the farm with his wife, two sons, and two wolfhounds.Along with Dr. Gillett, we're examining the complex world of women's hormones today. We'll be focusing on androgens like testosterone, DHEA, and dihydrotestosterone, and their profound impact on female health. Dr. Gillett provides insights on the role of binding globulins, hormone replacement therapy, and the interplay between insulin and androgens. We also discuss the challenges of menopausal weight gain, the benefits of GLP-1 medications for weight loss, and practical strategies anyone can use for maintaining lean body mass.



In this episode we discuss:

  • How androgens such as testosterone, DHEA, and dihydrotestosterone affect women's well-being.
  • Why sex hormone binding globulin (SHBG) is critical for hormone dynamics and stability.
  • Understanding the impact of thyroid binding globulin and cortisol binding globulin on hormone balance.
  • How hormone replacement therapy (HRT) influences women's bodies, especially regarding androgens.
  • Managing testosterone replacement therapy to avoid virilization symptoms like facial hair and voice changes.
  • The role of DHT blockers in managing androgen-related conditions.
  • How SHBG can be harnessed for overall hormone stability and health benefits.
  • Challenges of menopausal weight gain and how hormonal changes affect body composition.
  • Why integrating proper lifestyle habits is essential alongside GLP-1 medications for effective weight loss.
  • How to maintain lean body mass through hormone therapy and lifestyle changes.
  • How oral contraceptives and other synthetic hormones impact SHBG levels and overall hormone balance.
  • The significance of SHBG levels for individuals on hormone replacement therapy or contraceptives.
  • Exploring different forms of testosterone administration, including subcutaneous and intramuscular injections.
  • How estrogen and progesterone influence testosterone levels through negative feedback inhibition.
  • How poor sleep quality and hormonal changes contribute to menopausal weight gain.
  • The paradoxical effects of hormone replacement therapy on body composition and fat gain.
  • Why high SHBG must be paired with adequate hormone levels to avoid feeling unwell.
  • Discussing the challenges faced when SHBG levels are artificially high due to medication.


Download in iTunes or on your favorite podcast platforms.

Work withGillett Health here. 

Social handle@kylegillettmd Podcast Gillett Health

Motivation Podcast Cover.zip - 2.jpeg__PID:1106e527-881f-45a2-ba92-6c1850431c66

Find Karen Martel on Apply Podcast 

Karen Martel is a Certified Hormone Specialist and Transformational Nutrition Coach dedicated to empowering women through their health journeys.

As the host of the popular podcast The Hormone Solution, Karen tackles the complexities of hormonal health, weight loss resistance, and the challenges that come with perimenopause and menopause. Her mission is to disrupt outdated narratives surrounding women's health, providing reliable information and practical solutions that help women reclaim their vitality. With personal experience overcoming her own health struggles, Karen offers insights into hormone optimization and sustainable weight management strategies.

Join her as she engages in enlightening conversations with experts and shares actionable advice, all aimed at helping women navigate their unique hormonal landscapes with confidence and clarity. Tune in to discover how to embrace life's stages while enhancing overall well-being.

Progesterone: ProgestCalm - karenmartel
Progesterone: ProgestCalm - karenmartel
Progesterone: ProgestCalm - karenmartel
Progesterone: ProgestCalm - karenmartel
Progesterone: ProgestCalm - karenmartel
Progesterone: ProgestCalm - karenmartel
Progesterone: ProgestCalm - karenmartel
Progesterone: ProgestCalm - karenmartel

Progesterone: Progest Calm

$54.99

Listen to more

Midlife Fitness: Cutting Through the Hype and doing What Really Works with Ulrich Dempfle

Midlife Fitness: Cutting Through the Hype and doing What Really Works with Ulrich Dempfle

Mar 26, 2025
by
Karen Martel

Bored of the same old cardio routine that feels more like a chore than a benefit? What if you could transform your fitness in just five minutes? Ulrich Dempfle joins us today to introduce the CAROL Bike and REHIT technology, promising a cardio revolution. Join us as we explore the science behind barely breaking a sweat while reaping impressive fitness rewards. Can a 5-minute workout really improve your VO2 max by over 12% in just weeks? How can AI personalize your exercise routine for maximum results? Discover how the CAROL Bike addresses our evolutionary instincts to conserve energy and fits seamlessly into our busy lives. Wondering why Olympic athletes are raving about a stationary bike? Could this be the solution to the time-crunch dilemma we all face? This episode is packed with inspiring stories and actionable insights to shift your perspective on exercise and health forever.

Round Table with The Meno Besties: Meno Myths, Midlife Madness & The Hormone Truth Bombs You Need to Hear

Round Table with The Meno Besties: Meno Myths, Midlife Madness & The Hormone Truth Bombs You Need to Hear

Mar 24, 2025
by
Karen Martel

Are you tired of the myths and misinformation surrounding menopause? Ever wonder why hormone replacement therapy is so misunderstood? This episode goes right into the complex world of menopause, revealing truths that challenge outdated beliefs, guided by Zora Benhamou and Dr. Fiona Lovely. How does culture impact menopause experiences, and what misconceptions need to be shattered? Join us as we discuss the real implications of menopause beyond hot flashes. How do hormone changes affect brain and joint health, and why are they often overlooked? What are the global gaps in menopause knowledge, and how can we bridge them?

Compare0

              Terms & Conditions

              Karen Martel Hormone Solutions supplies products listed on the website, and in our stores under the following Terms and Conditions. Please read these Terms and Conditions, and our Privacy and Cookie Policies carefully before using any of our websites, or ordering from us.

              The Terms and Conditions apply to your use of any Karen Martel website and to any products you purchase from them; regardless of how you access the website, including any technologies or devices where our website is available to you at home, on the move or in store

              We reserve the right to update these Terms and Conditions at any time, and any updates affecting you or your purchases will be notified to you, by us in writing (via email), and on this page.

              The headings in these Conditions are for convenience only and shall not affect their interpretation.

              We recommend that you print and keep a copy of these Terms and Conditions for your future reference...