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NAD+ decline is a complex issue. There are several aspects of the Salvage Pathway (the cells main source of NAD+) which become less efficient as we age. Therefore, to increase our cellular NAD+ levels we need to take a whole-systems approach.
To do this the Nuchido TIME+ formulation is designed to:
- Enhance the NAD+ recycling capacity of the salvage pathway by increasing NAMPT enzyme levels
- Prevent NAD+ consumption by inhibiting the inflammatory enzyme CD38 (the largest NAD+ consumer)
- Reduce NAD+ wastage and further encourage recycling by limiting methylation
NAD+ AND MENOPAUSE
The average age a woman enters menopause is 51 and by this time her NAD+
levels will have declined drastically. The loss of estrogen and NAD+ combined
creates a perfect storm for cellular dysfunction
How does menopause accelerate biological aging?
One important function of estrogen is in regulating the immune system, and the loss of estrogen during menopause causes increased levels of chronic inflammation. Inflammation is known to be a key driver of cellular aging.
NAD+ is an exciting new area of research for menopause offering a solution for some of the most common menopause symptoms including:
Both NAD+ and estrogen contribute to mitochondrial function and normal energy production. During menopause, levels of these molecules become low leading to reduced energy production.
By increasing NAD+ energy production is increased.
Estrogen is important for optimal brain function and energy production in brain
cells. NAD+ is also critical for energy production and supporting brain health.
By increasing your NAD+ levels you can increase cellular energy levels and support your brain.
Accelerated biological aging
Hormones are important in regulating biological age (the rate at which cells are aging and functioning), with recent studies showing that peri/menopause can accelerate aging and rapidly increase a woman’s biological age.
NAD+ is known to promote youthful cellular function and reverse biological age
Listen to the podcast episode with NUCHIDO founder Nichola Conlon “The Elixir of Youth: The NAD+ Breakdown with Dr. Nichola Conlon.”