Cart 0

Sorry, looks like we don't have enough of this product.

Pair with
Is this a gift?
Congratulations! Your order qualifies for free shipping You are $200 away from free shipping.

Use coupon code WELCOME10 for 10% off your first order.

Subtotal Free
Shipping, taxes, and discount codes are calculated at checkout

Your Cart is Empty

Estro2 Rejuvenate Face Cream
Estro2 Rejuvenate Face Cream Ingredients
Face Products for Women

Estro2 Rejuvenate Face Cream

Regular price $59.99

BLACK FRIDAY SALE EVENT ON NOV 25TH - DEC 2ND

Grab your favourites and stack the savings with these coupon codes:

• 10% off any single hormone cosmetic cream — BF10
15% off any two — BF15
20% off when you bundle three — BF20

Support your most intimate tissue—naturally.

Estro2 Rejuvenate Face Cream is a bioidentical topical formula designed with perimenopausal and menopausal women in mind. This professional-grade cream contains a blend of USP-grade estradiol and estriol, crafted to complement your skincare and wellness routine.

The ingredients in this formula have been studied for their potential to:

  • Support skin health by promoting collagen production
  • Enhance elasticity and the appearance of fine lines and wrinkles
  • Promote a more radiant, youthful-looking complexion

Download our FREE eBook Product User Guide! 

Download our Quick Start Guide


* International shipping is unavailable for this product.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary. Always consult with your healthcare provider before starting any new supplement or skincare product.

Cruelty Free Fragrance Free Mineral Oil Free Paraben Free Phthalate Free Silicone Free Sulfate Free

Suggested Use

Highlights:

NEW precision dosing pump with MORE cream added per bottle compared to our previous version.

1.25 mg (.25mg estradiol and 1 mg Estriol) Bio-identical Estrogen per pump.

Maximum bioavailability.

Free from harmful preservatives.

How to Use: NEW precision dosing pump and 3.6 oz bottle!!

The new pump design gives you 4 times the precision, so now 4 pumps from the new bottle equal just 1 pump from the old bottle.

This allows for better control over your dosage, helping you get the perfect amount each time.

Dosage breakdown:

1 pump = .25 mg of estradiol + 1 mg of estriol.

For those of you using the cream for its amazing anti-aging skin benefits, 1 pump per day is typically enough to cover your face.

You’ll love the convenience and the improved application!

Face cream: Apply 1-2 pumps of face cream to your face and neck once daily. Massage gently until fully absorbed.


Body cream: Apply up to 2 pumps of body cream to your inner forearms twice daily. Rub arms together until fully absorbed.

This container: Each pump dose provides approximately 1 mg of estriol and 0.25 mg of estradiol. A 4-pump dose provides approximately 4 mg of estriol and 1 mg of estradiol.

Download our FREE product guidebook!

Tailor usage to your specific concern, whether it’s menopause, or aging skin.
Important Note: If you are using any form of estrogen, it is generally recommended to combine it with progesterone. Consider our Progest Calm, which contains 50 mg of progesterone cream.

Precautions and Side Effects: Always consult your doctor before use. Our natural BIEST cream, with 5mg per 4 pump dose, offers a 70+ day supply. Free from fillers and harmful ingredients, it incorporates Vitamin E, Aloe Vera, and Allantoin oil for enhanced skin rejuvenation. Made in the USA in a Kosher and FDA-inspected facility, Hormone Solutions by Karen Martel is a brand you can trust.

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Ingredients
  • Purified Water
  • Vegetable Glycerin
  • Aloe Vera Leaf Gel
  • Caprylic/Capric Triglyceride
  • Stearic Acid
  • Micronized Estriol USP
  • Micronized Estradiol USP
  • Olive Oil
  • Coconut Oil
  • Shea Butter
  • Sunflower Lecithin
  • Methylsulfonylmethane (MSM)
  • Stearyl Alcohol
  • Isopropyl Palmitate
  • Allantoin
  • Carbomer
  • Sodium Bicarbonate
  • Herbal-Active (Natural Preservative)

Bundle and Save

Purchase our flagship products together and get a discount!

Estro2 Rejuvenate Face Cream

As estrogen levels naturally decline in our late 40s and 50s, skin may appear less firm and hydrated. Estradiol and estriol—two gentle, bioidentical forms of estrogen—are known to support collagen structure, skin elasticity, and moisture balance. This topical formula is thoughtfully designed for mature skin, offering nurturing support during the hormonal transitions of midlife.

★★★★★

5-Star Reviews from Women Like You

The cream is so smooth and luxurious! It hydrates and seems to add volume to sagging skin near my mouth. Thank you for making this available to us!

Kim Pyper

Love this product. My face looks amazing. No fine lines feels moisturized. Can say-enough. So glad I found this face cream!

Donna Jordan

Amazing product! Easy application and rubs in so quickly without any residue or sticky feeling. My skin looks and feels amazing; I love the pure ingredients, and the most fantastic Customer Service Team is quick to respond to any questions you may have; you are never left hanging and in the online world that is a big plus!

Holly B.

 Our Product Mission: Helping Midlife Women Thrive

At Midlife Solutions, our mission is to create clean, effective, and easily accessible products that support women through every stage of midlife. Our formulations are made with integrity — no harmful chemicals or questionable ingredients. Every product is cruelty-free, toxin-free, and formulated with USP-grade hormones to help women feel vibrant, balanced, and confident in their skin again.

Your Midlife Quick Start Guide

Want to make the most of your hormones? Learn exactly how to use your products and understand what your body needs in peri and post-menopause.

Download our FREE eBook: The Product User Guide + Product Quick Start Cheat Sheet — your step-by-step roadmaps to midlife wellness, using our products correctly, and feeling your best.

FAQ

How can this product support me during menopause?

Midlife transitions can bring a range of physical and emotional changes. Estro2 Rejuvenate Cream is formulated with bioidentical estradiol and estriol, ingredients studied for their potential to support the skin and contribute to a sense of well-being. Many women choose to include topical estrogen in their wellness routines to complement healthy lifestyle practices and help them feel more balanced during this phase.

Always consult with a qualified healthcare provider before using hormone-based products, especially during perimenopause.

Can this cream improve the appearance of my skin as I age?

Topical estrogens like estriol and estradiol have been studied for their potential benefits on mature skin, including hydration, elasticity, and collagen support. Some research suggests they may contribute to improvements in skin texture, fine lines, and overall tone. While individual results may vary, Estro2 Rejuvenate is formulated with these ingredients to support your skincare goals during midlife.

Will applying this to my face affect my hormone levels?

Yes, applying topical estrogen to any area of the skin can be absorbed systemically. Even small doses may influence overall hormone levels, depending on factors such as dosage, skin thickness, and frequency of use.

We recommend consulting a healthcare provider to determine appropriate use for your individual situation, especially if you are still menstruating or cycling.

Why choose Estro2 Rejuvenate?

Estro2 Rejuvenate offers a thoughtful blend of USP-grade bioidentical hormones in a clean, professional-strength base. It’s crafted for precision dosing, suitable for both facial and body application. With quality ingredients and a wellness-forward formulation, it’s designed for those seeking to support their skin and well-being as part of a broader self-care routine.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Real Customers. Real Results.