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Why you will ❤️️ it!
- Restful sleep routines
- Cellular health and antioxidant activity
- Energy metabolism and immune response
- Mood and cognitive wellness
- Hormonal transitions during midlife
- Interact with neurotransmitters like GABA
- Support a relaxed mental state
- Contribute to sleep rhythm support
Progest Sleep: A Unique Topical Blend for Evening Wellness
There’s nothing quite like this—a topical oil combining USP-grade bioidentical progesterone and transdermal melatonin, crafted to complement your nighttime self-care ritual. This innovative formula is thoughtfully designed for women navigating perimenopause, menopause, or anyone seeking a calming addition to their evening routine.
Why These Two Ingredients?
Melatonin, often called the "sleep hormone," is naturally produced by the body and plays a role in maintaining circadian rhythms. Research has explored its connection to:
Melatonin levels tend to decline with age, while other hormonal signals like FSH may increase. Some wellness practitioners explore melatonin supplementation as part of a comprehensive approach to supporting daily balance.
Progesterone is another key hormone in the body, and its presence has been associated with a sense of calm and relaxation. Some studies suggest progesterone may:
Why Transdermal Delivery?
Transdermal application allows for gentle, sustained absorption, making it a convenient option for those looking to avoid pills or capsules. Compared to oral melatonin, this delivery method may offer more gradual uptake and consistent support throughout the night.
Is Progest Sleep Right for You?
If your evening routine feels disrupted by restlessness, shifting hormones, or changes in how you wind down, Progest Sleep may be a gentle, topical way to support your goals.
💡 Always consult with a qualified healthcare provider before beginning any product containing hormone-based ingredients like progesterone or melatonin, especially if pregnant, nursing, or managing a medical condition.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
FAQ
- Help regulate circadian rhythms
- Act as a powerful antioxidant to support cellular health
- Assist in maintaining healthy energy metabolism
- Support immune system balance
- Contribute to mood stability and emotional well-being
- For cycling women: many choose to use progesterone during the last 14 days of their menstrual cycle.
- For menopausal women: cycling is optional — some prefer nightly use, while others take periodic breaks.
Q1: What does melatonin do besides support sleep?
A:
While melatonin is best known for supporting restful sleep, research has explored its broader role in overall wellness. Studies suggest melatonin may also:
As melatonin levels naturally decline with age, many people explore gentle supplementation as part of their daily wellness strategy.
Always consult your healthcare provider before using any hormone-based product.
Q2: Can melatonin be absorbed through the skin?
A:
Yes, studies have shown that melatonin can be absorbed transdermally (through the skin). This method bypasses the digestive system and may offer gradual, sustained absorption compared to oral supplements, which typically have a shorter active window. Some users prefer this option for its convenience and steady release.
Q3: Can I take this oil orally?
A:
Progest Sleep is designed for topical use only. While the ingredients (MCT oil, melatonin, and USP-grade progesterone) are generally regarded as safe, the product is not formulated or flavored for oral consumption. For best results, apply as directed to the skin.
Q4: Is the progesterone in Progest Sleep bioidentical?
A:
Yes! We only use USP-grade bioidentical progesterone, which is molecularly identical to the progesterone naturally produced by the human body.
Q5: Should I cycle this product?
A:
Cycling use of progesterone-based products is often recommended to mirror the body’s natural hormone rhythms.
Consult a healthcare provider to determine the right schedule for your body.
Q6: The oil feels grainy or looks white — is that normal?
A:
Yes, this is completely normal. the oil can have a slightly grainy texture, which dissolves quickly when rubbed into the skin. The oil may also appear milky white due to the ingredients. Always shake well before use, as the hormones can naturally separate from the oil between applications.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Let customers speak for us
from 188 reviewsReally like this cream! It spreads nicely and I can see my sleep is better on my Fitbit. Thank you for making this cream available.

The cream is so smooth and luxurious! It hydrates and seems to add volume to sagging skin near my mouth. Thank you for making this available to us!

This really helped me to sleep better and feel more energized the next day. I also had fewer PMS symptoms. I highly recommend this product!

I love this cream. Under eye area looks so much better.

Love this product. Love that I can use a product that is transdermal

Love this product. My face looks amazing. No fine lines feels moisturized. Can say-enough. So glad I found this face cream

Once progest calm came back in stock it was delivered quickly
I have really enjoyed using the Estro 2rejuvenate cream. I layer it in my AM routine after vitamin C and before sunscreen. It layers beautifully.

LOVE IT!!!! Need I say more. I went to the doctor for OAB (over active bladder) and they gave me a prescription with so many potential side effects that I wouldn’t give it to my worst enemy (okay we’ll maybe 🤔). Any way Velvet V is helping and hoping to see even greater improvements.
Thank you!
Diane Drago-Cole
56 years old, just hit menopause and a competitive CrossFit athlete.

I am pretty new to bhrt and feel so comfortable with Karen's products. The cream feels so good and I am sleeping better at night. Looking forward to running my labs so see where my levels are. Feeling a difference in such a great way!!! Love this product!

Great product. It’s light and clean feeling. I use it before bed and it feel like it’s helping to balance my use of the estrogen cream.

Great feel- so soothing and velvety! Love the texture and it really helps the tissue inside and out without feeling sticky or messy.
